BERT6mA

Introduction

DNA modifications are related to biologically important processes and functions such as DNA replication, DNA repair, transcription, regulation of gene expression. N6-methyladenine (6mA) is one of the essential epigenetic modifications and is associated with several diseases. Therefore, the identification of 6mA is significant to understand epigenetic modification processes and reveal the epigenetic regulation related to the diseases. Several experimental methods were developed to detect the modifications. However, experimental methods are costly and time-consuming in common, and some of them have problems with sequencing quality. To reduce the experimental cost and compensate for the shortcomings of experimental methods, developing computational prediction models is valuable. This BERT6mA online website provides prediction using BERT with word2vec.